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Disruption of Ledgf/Psip1 Results in Perinatal Mortality and Homeotic Skeletal Transformations

PC4- and SF2-interacting protein 1 (Psip1)—also known as lens epithelium-derived growth factor (Ledgf)—is a chromatin-associated protein that has been implicated in transcriptional regulation, mRNA splicing, and cell survival in vitro, but its biological function in vivo is unknown. We identified an...

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Bibliographic Details
Main Authors: Sutherland, Heidi G., Newton, Kathryn, Brownstein, David G., Holmes, Megan C., Kress, Clémence, Semple, Colin A., Bickmore, Wendy A.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2006
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1592893/
https://ncbi.nlm.nih.gov/pubmed/16980622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00459-06
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