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Psip1/Ledgf p75 restrains Hox gene expression by recruiting both trithorax and polycomb group proteins

Trithorax and polycomb group proteins are generally thought to antagonize one another. The trithorax family member MLL (myeloid/lymphoid or mixed-lineage leukemia) is presumed to activate Hox expression, counteracting polycomb-mediated repression. PC4 and SF2 interacting protein 1 (PSIP1)/p75, also...

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Detalhes bibliográficos
Main Authors: Pradeepa, Madapura M., Grimes, Graeme R., Taylor, Gillian C.A., Sutherland, Heidi G., Bickmore, Wendy A.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4132756/
https://ncbi.nlm.nih.gov/pubmed/25056311
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku647
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