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MDM2 Promotes Cell Motility and Invasiveness by Regulating E-Cadherin Degradation

Gene amplification and protein overexpression of MDM2, which is often found in certain types of cancers, indicate that MDM2 plays an important role in tumorigenesis. Interestingly, several clinical reports have demonstrated that amplification of the MDM2 gene correlates with the metastatic stage. Us...

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Hlavní autoři: Yang, Jer-Yen, Zong, Cong S., Xia, Weiya, Wei, Yongkun, Ali-Seyed, Mohamed, Li, Zheng, Broglio, Kristine, Berry, Donald A., Hung, Mien-Chie
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2006
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1592879/
https://ncbi.nlm.nih.gov/pubmed/16980628
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00172-06
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