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A New Fork for Clinical Application:Targeting Forkhead Transcription Factors in Cancer

Forkhead O transcription factors (FOXO) playa pivotal role in the regulation of a myriad of cellular functions including cell cycle arrest, cell death, and protection from stress stimuli. Activation of cell survival pathways such as phosphoinositide-3-kinase/AKT/IKK or RAS/mitogen-activated protein...

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Bibliographic Details
Main Authors: Yang, Jer-Yen, Hung, Mien-Chie
Format: Artigo
Language:Inglês
Published: 2009
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2676228/
https://ncbi.nlm.nih.gov/pubmed/19188143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-08-0124
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