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Phosphorylation of FANCD2 on Two Novel Sites Is Required for Mitomycin C Resistance
The Fanconi anemia (FA) pathway is a DNA damage-activated signaling pathway which regulates cellular resistance to DNA cross-linking agents. Cloned FA genes and proteins cooperate in this pathway, and monoubiquitination of FANCD2 is a critical downstream event. The cell cycle checkpoint kinase ATR i...
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| Auteurs principaux: | , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Society for Microbiology
2006
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1592857/ https://ncbi.nlm.nih.gov/pubmed/16943440 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.02018-05 |
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