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ATR couples FANCD2 monoubiquitination to the DNA-damage response

Fanconi anemia (FA) is a multigenic autosomal recessive cancer susceptibility syndrome. The FA pathway regulates the monoubiquitination of FANCD2 and the assembly of damage-associated FANCD2 nuclear foci. How FANCD2 monoubiquitination is coupled to the DNA-damage response has remained undetermined....

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Bibliografiske detaljer
Main Authors: Andreassen, Paul R., D'Andrea, Alan D., Taniguchi, Toshiyasu
Format: Artigo
Sprog:Inglês
Udgivet: Cold Spring Harbor Laboratory Press 2004
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC514175/
https://ncbi.nlm.nih.gov/pubmed/15314022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1196104
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