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Hyperplasia and Spontaneous Tumor Development in the Gynecologic System in Mice Lacking the BRCA1-Δ11 Isoform
Alternative splicing in the BRCA1 locus generates multiple protein products including BRCA1-Δ11, which is identical to the BRCA1 full-length isoform (BRCA1-FL) except for the absence of exon 11. Mutation analysis using gene targeting to create null mutations or disrupt BRCA-FL has provided much of o...
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| Main Authors: | , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Microbiology
2006
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1592852/ https://ncbi.nlm.nih.gov/pubmed/16943438 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00796-06 |
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