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Complex Minisatellite Rearrangements Generated in the Total or Partial Absence of Rad27/hFEN1 Activity Occur in a Single Generation and Are Rad51 and Rad52 Dependent

Genomes contain tandem repeat blocks that are at risk of expansion or contraction. The mechanisms of destabilization of the human minisatellite CEB1 (arrays of 36- to 43-bp repeats) were investigated in a previously developed model system, in which CEB1-0.6 (14 repeats) and CEB1-1.8 (42 repeats) all...

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Hlavní autoři: Lopes, Judith, Ribeyre, Cyril, Nicolas, Alain
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2006
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1592832/
https://ncbi.nlm.nih.gov/pubmed/16914748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00649-06
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