Activation of Receptor Activator of NF-κB Ligand Gene Expression by 1,25-Dihydroxyvitamin D(3) Is Mediated through Multiple Long-Range Enhancers

RANKL is a tumor necrosis factor (TNF)-like factor secreted by mesenchymal cells, osteoblast derivatives, and T cells that is essential for osteoclastogenesis. In osteoblasts, RANKL expression is regulated by two major calcemic hormones, 1,25-dihydroxyvitamin D(3) [1,25(OH)(2)D(3)] and parathyroid h...

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Bibliographic Details
Main Authors: Kim, Sungtae, Yamazaki, Miwa, Zella, Lee A., Shevde, Nirupama K., Pike, J. Wesley
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2006
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Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1592822/
https://ncbi.nlm.nih.gov/pubmed/16914732
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00353-06
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