Anaplastic Lymphoma Kinase Is a Dependence Receptor Whose Proapoptotic Functions Are Activated by Caspase Cleavage

Anaplastic lymphoma kinase (ALK) is a receptor tyrosine kinase, initially discovered as part of the NPM-ALK fusion protein, resulting from the t(2;5) translocation that is frequently associated with anaplastic large-cell lymphomas. The native ALK protein is normally expressed in the developing and,...

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Détails bibliographiques
Auteurs principaux: Mourali, Jaouhar, Bénard, Alan, Lourenço, Filipe Calheiros, Monnet, Céline, Greenland, Catherine, Moog-Lutz, Christel, Racaud-Sultan, Claire, Gonzalez-Dunia, Daniel, Vigny, Marc, Mehlen, Patrick, Delsol, Georges, Allouche, Michèle
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2006
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Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1592804/
https://ncbi.nlm.nih.gov/pubmed/16880530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01515-05
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