p27(Kip1) and p130 Cooperate To Regulate Hematopoietic Cell Proliferation In Vivo

To investigate the potential functional cooperation between p27(Kip1) and p130 in vivo, we generated mice deficient for both p27(Kip1) and p130. In p27(Kip1)(−/−); p130(−/−) mice, the cellularity of the spleens but not the thymi is significantly increased compared with that of their p27(Kip1)(−/−) c...

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Main Authors: Soeiro, Inês, Mohamedali, Azim, Romanska, Hanna M., Lea, Nicholas C., Child, Emma S., Glassford, Janet, Orr, Stephen J., Roberts, Claudia, Naresh, Kikkeri N., Lalani, El-Nasir, Mann, David J., Watson, Roger J., Thomas, N. Shaun B., Lam, Eric W.-F.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2006
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1592787/
https://ncbi.nlm.nih.gov/pubmed/16880527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.02182-05
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