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p27(Kip1) and p130 Cooperate To Regulate Hematopoietic Cell Proliferation In Vivo

To investigate the potential functional cooperation between p27(Kip1) and p130 in vivo, we generated mice deficient for both p27(Kip1) and p130. In p27(Kip1)(−/−); p130(−/−) mice, the cellularity of the spleens but not the thymi is significantly increased compared with that of their p27(Kip1)(−/−) c...

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Detalhes bibliográficos
Main Authors: Soeiro, Inês, Mohamedali, Azim, Romanska, Hanna M., Lea, Nicholas C., Child, Emma S., Glassford, Janet, Orr, Stephen J., Roberts, Claudia, Naresh, Kikkeri N., Lalani, El-Nasir, Mann, David J., Watson, Roger J., Thomas, N. Shaun B., Lam, Eric W.-F.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2006
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1592787/
https://ncbi.nlm.nih.gov/pubmed/16880527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.02182-05
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