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Bloom Helicase and DNA Topoisomerase IIIα Are Involved in the Dissolution of Sister Chromatids
Bloom's syndrome (BS) is an autosomal disorder characterized by predisposition to a wide variety of cancers. The gene product whose mutation leads to BS is the RecQ family helicase BLM, which forms a complex with DNA topoisomerase IIIα (Top3α). However, the physiological relevance of the intera...
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| Päätekijät: | , , , , , , , , , , , , , |
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| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
American Society for Microbiology
2006
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1592785/ https://ncbi.nlm.nih.gov/pubmed/16880537 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00702-06 |
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