Bloom Helicase and DNA Topoisomerase IIIα Are Involved in the Dissolution of Sister Chromatids

Bloom's syndrome (BS) is an autosomal disorder characterized by predisposition to a wide variety of cancers. The gene product whose mutation leads to BS is the RecQ family helicase BLM, which forms a complex with DNA topoisomerase IIIα (Top3α). However, the physiological relevance of the intera...

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Hauptverfasser: Seki, Masayuki, Nakagawa, Takayuki, Seki, Takahiko, Kato, Genta, Tada, Shusuke, Takahashi, Yuriko, Yoshimura, Akari, Kobayashi, Takayuki, Aoki, Ayako, Otsuki, Makoto, Habermann, Felix A., Tanabe, Hideyuki, Ishii, Yutaka, Enomoto, Takemi
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2006
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Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1592785/
https://ncbi.nlm.nih.gov/pubmed/16880537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00702-06
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