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FoxA2, Nkx2.2, and PDX-1 Regulate Islet β-Cell-Specific mafA Expression through Conserved Sequences Located between Base Pairs −8118 and −7750 Upstream from the Transcription Start Site

The MafA transcription factor is both critical to islet β-cell function and has a unique pancreatic cell-type-specific expression pattern. To localize the potential transcriptional regulatory region(s) involved in directing expression to the β cell, areas of identity within the 5′ flanking region of...

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Hlavní autoři: Raum, Jeffrey C., Gerrish, Kevin, Artner, Isabella, Henderson, Eva, Guo, Min, Sussel, Lori, Schisler, Jonathan C., Newgard, Christopher B., Stein, Roland
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2006
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1592775/
https://ncbi.nlm.nih.gov/pubmed/16847327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00249-06
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