Islet β-Cell-Specific MafA Transcription Requires the 5′-Flanking Conserved Region 3 Control Domain

MafA is a key transcriptional activator of islet β cells, and its exclusive expression within β cells of the developing and adult pancreas is distinct among pancreatic regulators. Region 3 (base pairs −8118 to −7750 relative to the transcription start site), one of six conserved 5′ cis domains of th...

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Autori principali: Raum, Jeffrey C., Hunter, Chad S., Artner, Isabella, Henderson, Eva, Guo, Min, Elghazi, Lynda, Sosa-Pineda, Beatriz, Ogihara, Takeshi, Mirmira, Raghavendra G., Sussel, Lori, Stein, Roland
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology (ASM) 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2937551/
https://ncbi.nlm.nih.gov/pubmed/20584984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01396-09
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