5′-AMP-Activated Protein Kinase (AMPK) Is Induced by Low-Oxygen and Glucose Deprivation Conditions Found in Solid-Tumor Microenvironments

Low oxygen gradients (hypoxia and anoxia) are important determinants of pathological conditions under which the tissue blood supply is deficient or defective, such as in solid tumors. We have been investigating the relationship between the activation of hypoxia-inducible factor 1 (HIF-1), the primar...

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Detalhes bibliográficos
Main Authors: Laderoute, Keith R., Amin, Khalid, Calaoagan, Joy M., Knapp, Merrill, Le, Theresamai, Orduna, Juan, Foretz, Marc, Viollet, Benoit
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2006
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1592699/
https://ncbi.nlm.nih.gov/pubmed/16809770
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00166-06
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