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CCI-779 Inhibits Rhabdomyosarcoma Xenograft Growth by an Antiangiogenic Mechanism Linked to the Targeting of mTOR/Hif-1α/VEGF Signaling

Angiogenesis is one of the critical steps in tumor growth and metastasis. The goal of this study was to evaluate whether the antitumor activity of CCI-779 is related to antiangiogenic effects in vivo in tumors of mice bearing human rhabdomyosarcoma (RMS) xenografts. We now demonstrate that CCI-779 r...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Wan, Xiaolin, Shen, Na, Mendoza, Arnulfo, Khanna, Chand, Helman, Lee J
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Neoplasia Press Inc. 2006
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC1592447/
https://ncbi.nlm.nih.gov/pubmed/16790088
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