The novel mTOR inhibitor CCI-779 (temsirolimus) induces antiproliferative effects through inhibition of mTOR in Bel-7402 liver cancer cells

BACKGROUND: Liver cancer is one of the most frequent cancers in the world. Targeted therapy of cancer with specific inhibitors is developing and has shown promising antitumor efficacy. CCI-779 (temsirolimus), a specific inhibitor of mTOR (mammalian target of rapamycin), can block the mTOR signaling...

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Detalhes bibliográficos
Main Authors: Li, Shuyu, Liang, Yan, Wu, Manlin, Wang, Xiaojing, Fu, Haixia, Chen, Yuhao, Wang, Zhigang
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Primary Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3632488/
https://ncbi.nlm.nih.gov/pubmed/23537100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2867-13-30
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