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Inhibition of Mammalian Target of Rapamycin Signaling by CCI-779 (Temsirolimus) Induces Growth Inhibition and Cell Cycle Arrest in Cashmere Goat Fetal Fibroblasts (Capra hircus)
The mammalian target of rapamycin (mTOR) is a Ser/Thr kinase. It plays an evolutionarily conserved role in regulating cell growth, proliferation, survival, and metabolism via different cellular processes. The purpose of this study was to explore the inhibitory effects of CCI-779 (temsirolimus), a sp...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Mary Ann Liebert, Inc.
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3378953/ https://ncbi.nlm.nih.gov/pubmed/22320865 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/dna.2011.1559 |
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