Induction of utrophin gene expression by heregulin in skeletal muscle cells: Role of the N-box motif and GA binding protein

The modulation of utrophin gene expression in muscle by the nerve-derived factor agrin plausibly involves the trophic factor ARIA/heregulin. Here we show that heregulin treatment of mouse and human cultured myotubes caused a ≈2.5-fold increase in utrophin mRNA levels. Transient transfection experime...

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Hauptverfasser: Gramolini, Anthony O., Angus, Lindsay M., Schaeffer, Laurent, Burton, Edward A., Tinsley, Jonathon M., Davies, Kay E., Changeux, Jean-Pierre, Jasmin, Bernard J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The National Academy of Sciences 1999
Schlagworte:
Biological Sciences
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC15923/
https://ncbi.nlm.nih.gov/pubmed/10077665
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