Antihyperalgesic effects of infection with a preproenkephalin-encoding herpes virus
To test the utility of gene therapeutic approaches for the treatment of pain, a recombinant herpes simplex virus, type 1, has been engineered to contain the cDNA for an opioid peptide precursor, human preproenkephalin, under control of the human cytomegalovirus promoter. This virus and a similar rec...
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| Udgivet i: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
1999
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC15921/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10077663/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.6.3211 |
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