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Antihyperalgesic effects of infection with a preproenkephalin-encoding herpes virus

To test the utility of gene therapeutic approaches for the treatment of pain, a recombinant herpes simplex virus, type 1, has been engineered to contain the cDNA for an opioid peptide precursor, human preproenkephalin, under control of the human cytomegalovirus promoter. This virus and a similar rec...

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Autors principals: Wilson, Steven P., Yeomans, David C., Bender, Mary Ann, Lu, Ying, Goins, William F., Glorioso, Joseph C.
Format: Artigo
Idioma:Inglês
Publicat: The National Academy of Sciences 1999
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC15921/
https://ncbi.nlm.nih.gov/pubmed/10077663
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