Mechanism of increased iron absorption in murine model of hereditary hemochromatosis: Increased duodenal expression of the iron transporter DMT1

Hereditary hemochromatosis (HH) is a common autosomal recessive disorder characterized by tissue iron deposition secondary to excessive dietary iron absorption. We recently reported that HFE, the protein defective in HH, was physically associated with the transferrin receptor (TfR) in duodenal crypt...

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Autori principali: Fleming, Robert E., Migas, Mary C., Zhou, XiaoYan, Jiang, Jinxing, Britton, Robert S., Brunt, Elizabeth M., Tomatsu, Shunji, Waheed, Abdul, Bacon, Bruce R., Sly, William S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The National Academy of Sciences 1999
Soggetti:
Biological Sciences
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC15909/
https://ncbi.nlm.nih.gov/pubmed/10077651
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