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Distinct roles of doublecortin modulating the microtubule cytoskeleton

Doublecortin is a neuronal microtubule-stabilising protein, mutations of which cause mental retardation and epilepsy in humans. How doublecortin influences microtubule dynamics, and thereby brain development, is unclear. We show here by video microscopy that purified doublecortin has no effect on th...

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Detalles Bibliográficos
Main Authors: Moores, Carolyn A, Perderiset, Mylène, Kappeler, Caroline, Kain, Susan, Drummond, Douglas, Perkins, Stephen J, Chelly, Jamel, Cross, Rob, Houdusse, Anne, Francis, Fiona
Formato: Artigo
Idioma:Inglês
Publicado: 2006
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1590004/
https://ncbi.nlm.nih.gov/pubmed/16957770
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601335
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