Distinct roles of doublecortin modulating the microtubule cytoskeleton

Doublecortin is a neuronal microtubule-stabilising protein, mutations of which cause mental retardation and epilepsy in humans. How doublecortin influences microtubule dynamics, and thereby brain development, is unclear. We show here by video microscopy that purified doublecortin has no effect on th...

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Hauptverfasser: Moores, Carolyn A, Perderiset, Mylène, Kappeler, Caroline, Kain, Susan, Drummond, Douglas, Perkins, Stephen J, Chelly, Jamel, Cross, Rob, Houdusse, Anne, Francis, Fiona
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2006
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1590004/
https://ncbi.nlm.nih.gov/pubmed/16957770
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601335
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