GLI3 mutations in human disorders mimic Drosophila Cubitus interruptus protein functions and localization

Truncation mutations of the GLI3 zinc finger transcription factor can cause Greig cephalopolysyndactyly syndrome (GCPS), Pallister–Hall syndrome (PHS), and postaxial polydactyly type A (PAP-A). GLI3 is homologous to Drosophila Cubitus interruptus (Ci), which regulates the patched (ptc), gooseberry (...

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Dades bibliogràfiques

Publicat a:	Proc Natl Acad Sci U S A
Autors principals:	Shin, Sang Hoon, Kogerman, Priit, Lindström, Erika, Toftgárd, Rune, Biesecker, Leslie G.
Format:	Artigo
Idioma:	Inglês
Publicat:	National Academy of Sciences 1999
Matèries:	Biological Sciences
Accés en línia:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC15863/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10077605/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.6.2880
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