The Acetyltransferase Activity of CBP Is Required for wingless Activation and H4 Acetylation in Drosophila melanogaster

CBP is a critical coactivator of transcription, but little is understood about the importance of its intrinsic acetyltransferase (AT) activity in gene activation in vivo. We show that the intrinsic AT function of CBP in Drosophila melanogaster (dCBP) is necessary to maintain a dCBP overexpression ph...

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Detalhes bibliográficos
Main Authors: Ludlam, William H., Taylor, Matthew H., Tanner, Kirk G., Denu, John M., Goodman, Richard H., Smolik, Sarah M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2002
Assuntos:
Transcriptional Regulation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC133831/
https://ncbi.nlm.nih.gov/pubmed/11997517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.11.3832-3841.2002
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