The Acetyltransferase Activity of CBP Is Required for wingless Activation and H4 Acetylation in Drosophila melanogaster

CBP is a critical coactivator of transcription, but little is understood about the importance of its intrinsic acetyltransferase (AT) activity in gene activation in vivo. We show that the intrinsic AT function of CBP in Drosophila melanogaster (dCBP) is necessary to maintain a dCBP overexpression ph...

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Détails bibliographiques

Publié dans:	Mol Cell Biol
Auteurs principaux:	Ludlam, William H., Taylor, Matthew H., Tanner, Kirk G., Denu, John M., Goodman, Richard H., Smolik, Sarah M.
Format:	Artigo
Langue:	Inglês
Publié:	Taylor & Francis 2002
Sujets:	Transcriptional Regulation
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC133831/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11997517/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.22.11.3832-3841.2002
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