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Selective fluorescent imaging of superoxide in vivo using ethidium-based probes

The putative oxidation of hydroethidine (HE) has become a widely used fluorescent assay for the detection of superoxide in cultured cells. By covalently joining HE to a hexyl triphenylphosphonium cation (Mito-HE), the HE moiety can be targeted to mitochondria. However, the specificity of HE and Mito...

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Main Authors: Robinson, Kristine M., Janes, Michael S., Pehar, Mariana, Monette, Jeffrey S., Ross, Meredith F., Hagen, Tory M., Murphy, Michael P., Beckman, Joseph S.
פורמט: Artigo
שפה:Inglês
יצא לאור: National Academy of Sciences 2006
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC1586181/
https://ncbi.nlm.nih.gov/pubmed/17015830
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0601945103
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