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CHYMOTRYPSIN C (CALDECRIN) STIMULATES AUTOACTIVATION OF HUMAN CATONIC TRYPSINOGEN
Trypsin-mediated trypsinogen activation (autoactivation) facilitates digestive zymogen activation in the duodenum, but may precipitate pancreatitis if occurs prematurely in the pancreas. Autoactivation of human cationic trypsinogen is inhibited by a repulsive electrostatic interaction between the un...
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| Main Authors: | , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2006
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1586167/ https://ncbi.nlm.nih.gov/pubmed/16505482 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M600124200 |
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