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CHYMOTRYPSIN C (CALDECRIN) STIMULATES AUTOACTIVATION OF HUMAN CATONIC TRYPSINOGEN

Trypsin-mediated trypsinogen activation (autoactivation) facilitates digestive zymogen activation in the duodenum, but may precipitate pancreatitis if occurs prematurely in the pancreas. Autoactivation of human cationic trypsinogen is inhibited by a repulsive electrostatic interaction between the un...

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Main Authors: Nemoda, Zsófia, Sahin-Tóth, Miklós
格式: Artigo
語言:Inglês
出版: 2006
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1586167/
https://ncbi.nlm.nih.gov/pubmed/16505482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M600124200
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