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DNA replication in vertebrates requires a homolog of the Cdc7 protein kinase

CDC7 is an essential gene required for DNA replication in Saccharomyces cerevisiae. Cdc7p homologs have recently been identified in vertebrates, but their role in DNA replication has not yet been addressed. Here we show that antibodies to the Xenopus laevis homolog, xCdc7, interfere with DNA replica...

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Détails bibliographiques
Auteurs principaux: Roberts, B. Tibor, Ying, Carol Y., Gautier, Jean, Maller, James L.
Format: Artigo
Langue:Inglês
Publié: The National Academy of Sciences 1999
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC15849/
https://ncbi.nlm.nih.gov/pubmed/10077591
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