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DNA replication in vertebrates requires a homolog of the Cdc7 protein kinase

CDC7 is an essential gene required for DNA replication in Saccharomyces cerevisiae. Cdc7p homologs have recently been identified in vertebrates, but their role in DNA replication has not yet been addressed. Here we show that antibodies to the Xenopus laevis homolog, xCdc7, interfere with DNA replica...

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Detalhes bibliográficos
Main Authors: Roberts, B. Tibor, Ying, Carol Y., Gautier, Jean, Maller, James L.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC15849/
https://ncbi.nlm.nih.gov/pubmed/10077591
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