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Sequence-specific RNA binding mediated by the RNase PH domain of components of the exosome
We have previously demonstrated that PM-Scl-75, a component of the human exosome complex involved in RNA maturation and mRNA decay, can specifically interact with RNAs containing an AU-rich instability element. Through the analysis of a series of deletion mutants, we have now shown that a 266 amino...
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| Hlavní autoři: | , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Cold Spring Harbor Laboratory Press
2006
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1581985/ https://ncbi.nlm.nih.gov/pubmed/16912217 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.144606 |
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