Tumors induce a subset of inflammatory monocytes with immunosuppressive activity on CD8(+) T cells

Active suppression of tumor-specific T lymphocytes can limit the efficacy of immune surveillance and immunotherapy. While tumor-recruited CD11b(+) myeloid cells are known mediators of tumor-associated immune dysfunction, the true nature of these suppressive cells and the fine biochemical pathways go...

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Detalhes bibliográficos
Main Authors: Gallina, Giovanna, Dolcetti, Luigi, Serafini, Paolo, Santo, Carmela De, Marigo, Ilaria, Colombo, Mario P., Basso, Giuseppe, Brombacher, Frank, Borrello, Ivan, Zanovello, Paola, Bicciato, Silvio, Bronte, Vincenzo
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2006
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1578632/
https://ncbi.nlm.nih.gov/pubmed/17016559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI28828
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