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Isolation of peptide aptamers that inhibit intracellular processes

We have developed a method for isolation of random peptides that inhibit intracellular processes in bacteria. A library of random peptides expressed as fusions to Escherichia coli thioredoxin (aptamers) were expressed under the tight control of the arabinose-inducible P(BAD) promoter. A selection wa...

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Detalhes bibliográficos
Main Authors: Blum, Jonathan H., Dove, Simon L., Hochschild, Ann, Mekalanos, John J.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC15785/
https://ncbi.nlm.nih.gov/pubmed/10688899
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