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Partitioning of Anesthetics into a Lipid Bilayer and their Interaction with Membrane-Bound Peptide Bundles

Molecular dynamics simulations have been performed to investigate the partitioning of the volatile anesthetic halothane from an aqueous phase into a coexisting hydrated bilayer, composed of 1,2-dioleoyl-sn-glycero-3-phosphocholine (DOPC) lipids, with embedded α-helical peptide bundles based on the m...

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Detalles Bibliográficos
Main Authors: Vemparala, Satyavani, Saiz, Leonor, Eckenhoff, Roderic G., Klein, Michael L.
Formato: Artigo
Idioma:Inglês
Publicado: Biophysical Society 2006
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1578482/
https://ncbi.nlm.nih.gov/pubmed/16877515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.106.085324
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