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Optimization and Evaluation of a Coarse-Grained Model of Protein Motion Using X-Ray Crystal Data

Simple coarse-grained models, such as the Gaussian network model, have been shown to capture some of the features of equilibrium protein dynamics. We extend this model by using atomic contacts to define residue interactions and introducing more than one interaction parameter between residues. We use...

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Bibliografski detalji
Glavni autori: Kondrashov, Dmitry A., Cui, Qiang, Phillips, George N.
Format: Artigo
Jezik:Inglês
Izdano: Biophysical Society 2006
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1578481/
https://ncbi.nlm.nih.gov/pubmed/16891367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.106.085894
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