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Biphasic Modulation of Ryanodine Receptors by Sulfhydryl Oxidation in Rat Ventricular Myocytes
To understand better the modulation of ryanodine receptors (RyRs) during oxidative stress, the effect of 4,4′-dithiodipyridine (DTDP), a cell-permeant and thiol-reactive oxidant, on global Ca(2+) signal and spontaneous Ca(2+) sparks of rat ventricular myocytes was investigated. It was shown that a b...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Biophysical Society
2006
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1578479/ https://ncbi.nlm.nih.gov/pubmed/16877504 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.106.087338 |
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