Carbonic anhydrase inhibitor suppresses invasion of renal cancer cells in vitro

Acidification of the extracellular milieu of malignant tumors is reported to increase the invasive behavior of cancer cells. In normal tissues, production of acid is catalyzed by carbonic anhydrases (CAs), some of which are known to be overexpressed in certain cancers. To investigate the functional...

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Detalles Bibliográficos

Publicado en:	Proc Natl Acad Sci U S A
Principais autores:	Parkkila, Seppo, Rajaniemi, Hannu, Parkkila, Anna-Kaisa, Kivelä, Jyrki, Waheed, Abdul, Pastoreková, Silvia, Pastorek, Jaromir, Sly, William S.
Formato:	Artigo
Idioma:	Inglês
Publicado:	National Academy of Sciences 2000
Assuntos:	Biological Sciences
Acceso en liña:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC15781/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10688890/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.040554897
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