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Fusion proteins of Hsp70 with tumor-associated antigen acting as a potent tumor vaccine and the C-terminal peptide-binding domain of Hsp70 being essential in inducing antigen-independent anti-tumor response in vivo
Hsp70s are a family of ATP-dependent chaperones of relative molecular mass around 70 kDa. Immunization of mice with Hsp70 isolated from tumor tissues has been proved to elicit specific protective immunity against the original tumor challenge. In this work, we investigated whether Hsp70 can be used a...
সংরক্ষণ করুন:
প্রধান লেখক: | , |
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বিন্যাস: | Artigo |
ভাষা: | Inglês |
প্রকাশিত: |
Cell Stress Society International
2006
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বিষয়গুলি: | |
অনলাইন ব্যবহার করুন: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1576472/ https://ncbi.nlm.nih.gov/pubmed/17009594 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1379/CSC-191R.1 |
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