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Tumor-Derived Inducible Heat Shock Protein 70 (HSP70) is an Essential Component of Anti-Tumor Immunity

The anti-apoptotic function and tumor-associated expression of HSP70 is consistent with HSP70 functioning as a survival factor to promote tumorigenesis. However, its immunomodulatory activities to induce anti tumor immunity predict the suppression of tumor growth. Using the Hsp70.1/3(−/−) (Hsp70(−/−...

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Publicat a:Oncogene
Autors principals: Dodd, Keela, Nance, Stephanie, Quezada, Melanie, Janke, Laura, Morrison, Jeffrey B, Williams, Richard T, Beere, Helen M
Format: Artigo
Idioma:Inglês
Publicat: 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4259895/
https://ncbi.nlm.nih.gov/pubmed/24662819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2014.63
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