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HSP70 peptide-bearing and peptide-negative preparations act as chaperokines

We recently elucidated a novel function for the 70-kDa heat shock protein (HSP70) as a chaperone and a cytokine, a chaperokine in human monocytes. Here we show that peptide-bearing and peptide-negative HSP70 preparations isolated from EMT6 mammary adenocarcinoma cells (EMT6-HSP70) act as chaperokine...

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Detalhes bibliográficos
Main Authors: Asea, Alexzander, Kabingu, Edith, Stevenson, Mary Ann, Calderwood, Stuart K.
Formato: Artigo
Idioma:Inglês
Publicado em: Cell Stress Society International 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC312872/
https://ncbi.nlm.nih.gov/pubmed/11189447
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