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Dual regulation of myofilament Ca(2+) sensitivity by levosimendan in normal and acidotic conditions in aequorin-loaded canine ventricular myocardium
1. Experiments were carried out in canine ventricular trabeculae loaded with aequorin to investigate the effects of levosimendan {(R)-([4-(1,4,5,6-tetrahydro-4-methyl-6-oxo-3-pyridazinyl)phenyl]-hydrazono)-propanedinitrile} on contractile force and Ca(2+) transients in normal and acidotic conditions...
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| Autori principali: | , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2005
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1576237/ https://ncbi.nlm.nih.gov/pubmed/15951828 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0706292 |
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