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Differential action of a protein tyrosine kinase inhibitor, genistein, on the positive inotropic effect of endothelin-1 and norepinephrine in canine ventricular myocardium

1. Experiments were carried out in isolated canine ventricular trabeculae and acetoxymethylester of indo-1-loaded single myocytes to elucidate the role of protein tyrosine kinase (PTK) in the inotropic effect of endothelin-1 (ET-1) induced by crosstalk with norepinephrine (NE). The PTK inhibitor gen...

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Detalhes bibliográficos
Main Authors: Chu, Li, Zhang, Jian-Xin, Norota, Ikuo, Endoh, Masao
Formato: Artigo
Idioma:Inglês
Publicado em: 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1576021/
https://ncbi.nlm.nih.gov/pubmed/15655501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0706097
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