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Tramadol produces outward currents by activating μ-opioid receptors in adult rat substantia gelatinosa neurones
1. An action of a tramadol metabolite, mono-O-dimethyl-tramadol (M1), on substantia gelatinosa (SG) neurones in adult rat spinal cord slices was examined by using the whole-cell patch-clamp technique. 2. In 41% of the neurones examined, superfusing M1 produced an outward current at −70 mV; this resp...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1576176/ https://ncbi.nlm.nih.gov/pubmed/15834442 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0706225 |
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