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Effect of mast cell chymase inhibitor on the development of scleroderma in tight-skin mice

1. Although the pathogenesis of scleroderma is not fully understood, activation of connective-tissue-type mast cells (CTMCs) has been implicated in various fibrotic diseases. 2. Our previous study showed that the number of CTMCs was markedly increased during fibrous proliferation in the skin of a sc...

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Autors principals: Shiota, Naotaka, Kakizoe, Eiichi, Shimoura, Keiko, Tanaka, Tetsuya, Okunishi, Hideki
Format: Artigo
Idioma:Inglês
Publicat: 2005
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1576161/
https://ncbi.nlm.nih.gov/pubmed/15806109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0706209
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