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Elevated expression of isopeptide bond cross-links contributes to fibrosis in scleroderma and the healing wounds of tight skin mice

Scleroderma is a chronic disease characterized by excessive tissue fibrosis. Recent studies indicate that cultured dermal fibroblasts isolated from patients produce excessive amounts of collagen and other extracellular matrix components. In this study, we investigated the mechanism(s) of abnormal ex...

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Detalhes bibliográficos
Main Authors: Sullivan, Janson C., Kakati, Donny D., Carter, Elliot, Boyd, Amy K., Kyriakides, Themis R., Agah, Azin
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2673953/
https://ncbi.nlm.nih.gov/pubmed/19128265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1524-475X.2008.00420.x
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