TNFα reduces tachykinin, PGE(2)-dependent, relaxation of the cultured mouse trachea by increasing the activity of COX-2

1. Chronic inflammation is a central feature of asthma. The inflammatory cytokine tumour necrosis factor α (TNFα) has been implicated in this disease, and is known to alter airway smooth muscle functionally. 2. The aim of this study was to investigate the influence of TNFα on tachykinin-induced airw...

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Detalhes bibliográficos
Main Authors: Bachar, Ofir, Rose, Andrew C, Adner, Mikael, Wang, Xudong, Prendergast, Clodagh E, Kempf, Ashley, Shankley, Nigel P, Cardell, Lars-Olaf
Formato: Artigo
Idioma:Inglês
Publicado em: 2004
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Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1575996/
https://ncbi.nlm.nih.gov/pubmed/15665861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0706067
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