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PGE(2) maintains the tone of the guinea pig trachea through a balance between activation of contractile EP(1) receptors and relaxant EP(2) receptors

BACKGROUND AND PURPOSE: The guinea pig trachea (GPT) is commonly used in airway pharmacology. The aim of this study was to define the expression and function of EP receptors for PGE(2) in GPT as there has been ambiguity concerning their role. EXPERIMENTAL APPROACH: Expression of mRNA for EP receptor...

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Detalhes bibliográficos
Main Authors: Säfholm, J, Dahlén, S-E, Delin, I, Maxey, K, Stark, K, Cardell, L-O, Adner, M
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3631371/
https://ncbi.nlm.nih.gov/pubmed/22934927
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2012.02189.x
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